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. 2016 Oct 27;7:496. doi: 10.3389/fphys.2016.00496

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Copyright © 2016 Jousset, Maguy, Rohr and Kucera.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential effects of the intercellular coupling and of the ion channel repertoire of endogenous MFBs on conduction. (A) Effects of increased coupling (CMC-MFB/MFB-MFB coupling set to normal CMC values, i.e., 100% γ_CMC−CMC; solid line) as opposed to control levels of coupling (dashed line; data from Figure 3) on CV, RMP and dV/dt_max. (B) Effects of replacing the ion channel repertoire of MFBs with that of CMCs (i.e., generation of “excitable MFBs”; dashed purple lines) as compared to the control situation (dashed green lines; data form Figure 3). Data represent the mean of 5 simulations.