Figure 3.

Metabolic characterization of siRNA-treated mice during metabolic cage analysis (A–D, n = 10) and ipGTT (E–F). (A) Food intake (left) and liquid consumption (with 6% sucrose, right) during light- and dark-phase (repeated measurement ANOVA with Bonferroni's multiple comparisons test). (B) Locomotor activity. (C) Energy expenditure. (D) Respiratory exchange ratio (VCO₂/VO₂). (E) Plasma glucose during ipGTT (n = 16). (H) According insulin levels during ipGTT (n = 15). Data represent mean ± SEM. Grey background indicates dark-phase.