Fig. 3.

Embryo screening and selection using NICS from a patient carrying a balanced translocation of chr14/15. A total of three embryos successfully developed to the blastocyst stage, and D3–D5 culture medium from each embryo was collected for the NICS assay to screen for chromosomal abnormalities. (A and B) Embryos showed chromosomal abnormalities with chr14/15 and therefore could not be transferred. (C) An embryo showed balanced chromosomal composition and was therefore transferred into the uterus of the patient, resulting in a successful pregnancy and a healthy live birth.