Fig. S8.

Near-complete tumor necrosis were achieved for all HCCs except the one in the caudate lobe, after treatment with CHAL and TPZ. Gross appearance and histopathology examination of two tumors in an HBx transgenic mouse treated with transient CHAL and TPZ (3 mg/kg) for 21 d. One tumor locates in middle-right lobe (marked with black dashed circle) showed near-complete necrosis (Right), but the other locates in caudate lobe (marked with blue dashed circle) did not show necrosis (Lower Left). (Scale bars: 0.2 mm.)