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. 2016 Sep 29;113(42):11829–11834. doi: 10.1073/pnas.1610472113

Table 1.

Demographic information, pathological stage and diagnosis, lesions seen by white light, and fluorescence imaging

Case no. Sex/age (y) Pathological stage Pathological diagnosis Grade Lesion number White light diagnosis Fluorescence imaging
1 M/63 pT3aN1 Infiltrating high-grade urothelial carcinoma, CIS and necrosis HGI 1 + +
2 M/61 pT0N0 Diverticulum with urothelial atypia and treatment effects + +
3 F/84 ypT3bN0 Invasive high-grade urothelial carcinoma HGI 2 + +
Invasive high-grade urothelial carcinoma and necrosis HGI 3 + +
4 M/51 pT2aN1 Residual infiltrative high-grade urothelial carcinoma micropapillary features, dysplasia and necrosis HGI 4 + +
5 M/69 pTaN0 Noninvasive high-grade papillary carcinoma HGN 5 + +
6 M/65 pT1N0 Residual invasive high-grade urothelial carcinoma, CIS and necrosis HGI 6 + +
CIS CIS 7 + +
CIS CIS 8 + +
7 M/61 pT1N0 Focally invasive high-grade urothelial carcinoma, necrosis HGI 9 + +
8 M/79 pT1N0 Dysplasia DIS 10 − +
Treatment effect and CCCG − +
9 M/74 pT0N0 CCCG − +
10 F/82 pT1N0 Noninvasive high-grade urothelial carcinoma HGN 11 + +
Invasive high-grade urothelial carcinoma HGI 12 + −
CIS CIS 13 − +
CIS and CCCG CIS 14 − +
11 M/68 pTisN0 CIS and CCCG CIS 15 + +
CIS CIS 16 − +
12 M/71 pTisN0 Noninvasive high-grade urothelial carcinoma HGN 17 + +
Noninvasive high-grade urothelial carcinoma HGN 18 + +
CIS CIS 19 − +
CIS CIS 20 − +
13* M/66 pT3N1 Invasive high-grade urothelial carcinoma + ICG-Cys
Ulceration, necrosis, CCCG +
14 M/66 pT1N0 Noninvasive high-grade urothelial carcinoma HGN 21 + +
15 M/57 pT1N0 Invasive high-grade urothelial carcinoma HGI 22 + +
16 F/77 pTisN0 CIS with early invasion CIS 23 + +
CIS with early invasion CIS 24 − +
17† M/57 pT1bN0 Invasive high-grade urothelial carcinoma HGI 25 + +
CIS with early invasion CIS 26 + +
Necrosis and treatment effect + +
18† M/72 pT3aN0 Invasive high-grade urothelial carcinoma, CIS HGI 27 + +
Necrosis and treatment effect in diverticulum + −
19 M/64 pT2aN0 Invasive high-grade urothelial carcinoma, CIS, Necrosis and treatment effect + ICG-Cys
20 M/63 ypT0N0 CCCG and reactive changes in scar + ICG-Cys
21 M/74 pT3aN0 Invasive high-grade urothelial carcinoma in scar HGI 28 + +
Necrosis + +
22† M/66 ypT3aN0 Invasive high-grade urothelial carcinoma with neuroendocrine features HGI 29 + +

+, Lesion was detected by white light or fluorescence imaging; −, lesion was not detected by white light or fluorescence imaging.

*

Forty micromolar of 80 mL construct was used for instillation.

†

Four micromolar of 80 mL construct was used for instillation.