Table 1.
Age band, years | Weight for age | PQ dose mg base | Underdose | Therapeutic dose | Supratherapeutic dose | PQ mg base/kg | ||||
---|---|---|---|---|---|---|---|---|---|---|
1st | median | 99th | n (%) | n (%) | n (%) | 1st | median | 99th | ||
0.5–4 (n = 5640) | 6.5 | 11.0 | 17.1 | 2.5 | 89 (1.58) | 5,494 (97.41) | 57 (1.01) | 0.15 | 0.23 | 0.38 |
5–9 (n = 1669) | 11.0 | 17.0 | 28.8 | 5 | 5 (0.3) | 1,511 (90.53) | 153 (9.17) | 0.18 | 0.29 | 0.45 |
10–14 (n = 1508) | 19.0 | 28.0 | 49.0 | 7.5 | 8 (0.53) | 1473 (97.68) | 27 (1.79) | 0.15 | 0.27 | 0.39 |
≥15 (n = 19,321) | 36.0 | 51.1 | 74.9 | 15 | 0 | 18,489 (95.69) | 832 (4.31) | 0.20 | 0.29 | 0.42 |
Corresponding mg base/kg doses of PQ are shown for the 1st, 50th (median), and 99th centiles