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. 2016 Oct 27;14:171. doi: 10.1186/s12916-016-0701-8

Table 1.

Summary of the proportions of individuals who would receive a primaquine (PQ) dose within the defined therapeutic dosing range of 0.15–0.38 mg base/kg body weight, an underdose (<0.15 mg base/kg), and a supratherapeutic dose (>0.38 mg base/kg)

Age band, years Weight for age PQ dose mg base Underdose Therapeutic dose Supratherapeutic dose PQ mg base/kg
1st median 99th n (%) n (%) n (%) 1st median 99th
0.5–4 (n = 5640) 6.5 11.0 17.1 2.5 89 (1.58) 5,494 (97.41) 57 (1.01) 0.15 0.23 0.38
5–9 (n = 1669) 11.0 17.0 28.8 5 5 (0.3) 1,511 (90.53) 153 (9.17) 0.18 0.29 0.45
10–14 (n = 1508) 19.0 28.0 49.0 7.5 8 (0.53) 1473 (97.68) 27 (1.79) 0.15 0.27 0.39
≥15 (n = 19,321) 36.0 51.1 74.9 15 0 18,489 (95.69) 832 (4.31) 0.20 0.29 0.42

Corresponding mg base/kg doses of PQ are shown for the 1st, 50th (median), and 99th centiles