Fig. 2.

Genomic information in the flow of cancer care. This simplified flow diagram illustrates the process of information gathering and decision making that characterizes the standard model of interventional oncology care. In particular, this model is applicable to the treatment, monitoring, and re-treatment phases of oncology care. In blue are primarily the information gathering steps, and in green are the active decision making and intervention steps. This process is inherently iterative, usually on a pre-planned schedule such as assessment of treatment response after 8 weeks of therapy, or surveillance monitoring on a quarterly basis. Each step of this process can be captured by one or more FHIR Resources/Profiles, which are shown in italics in parentheses. CDS Hooks is a special implementation of FHIR for clinical decision support purposes (see text for details)