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. 2016 Sep 8;22:664–673. doi: 10.2119/molmed.2016.00169

Figure 6.

Figure 6.

Invasion of ECM-like Matrigel™ by tumorigenic cell lines. Each cell line’s untreated cells were compared with MCF-7 untreated control cells to determine invasive potential. P values show that all three colorectal cancer cell lines had an increase in invasive potential compared to MCF-7. After treatment with the anti-LRP/LR-specific antibody, P values showed significantly decreased adhesive potential compared to MCF-7 control cells: SW-480 by 54%, HT-29 by 60% and DLD-1 by 69%. The control antibody IgG1-HD37 did not affect the invasive potential of the tumorigenic cell lines as expected.