Figure 1.

Effects of Ang II on the endoglin expression in cultured CFs. (A) Exogenous administration of angiotensin II (Ang II) increased the endoglin protein expression. Representative Western blot for endoglin in CFs following exogenous Ang II (10 nM) administration was for various periods of time. (B) Exogenous Ang II administration increased the endoglin mRNA expression in 4 hrs, and Epigallocatechin‐3‐O‐gallate attenuated endoglin expression in a concentration‐dependent manner. The detailed procedures for Western blot analysis and Northern blot analysis were described in Methods section. *P < 0.05 versus control (the repeated number was 3 per group). CFs, Cardiac fibroblasts.