Table 1.

Effect of hypoxanthine on serum lipids in Apoe KO and C57BL/6 mice

	WT (n = 6)	WT‐Hx (n = 8)	Apoe KO (n = 6)	Apoe KO‐Hx (n = 8)
Bodyweight	26.3 ± 1.2	26.0 ± 0.6	27.1 ± 0.8	26.8 ± 0.6
Total cholesterol (mg/dl)	144 ± 8	136 ± 3	370 ± 17*	1578 ± 172* , †
Triglyceride (mg/dl)	34 ± 1	36 ± 2	83 ± 12	150 ± 81

*P < 0.001 versus WT mice, ^† P < 0.001 versus Apoe KO mice. Data are expressed as mean ± S.E.M. Data were analysed with one‐way anova and Bonferroni post hoc test; WT, C57BL/6 wild type; Hx: hypoxanthine.