Table 1.
Residue | k ex [s−1][a] | p B [%][b] | |Δ |[ppm][c] | |
---|---|---|---|---|
A‐site RNA 1 a/b 285 K | C7 C9 A10 A92 A93 G94 U95 | 1880±140 | 4.06±1.28 | 0.24±0.07 0.15±0.08 0.22±0.05 0.14±0.07 0.24±0.05 0.34±0.07 0.29±0.06 |
cTAR DNA 2 a/b 298 K | G4 A5 C19 G20 A21 C22 C23 | 525±59 | 1.0±0.1 | 0.25±0.02 0.49±0.03 0.22±0.01 0.20±0.02 0.56±0.03 0.34±0.02 0.24±0.01 |
[a] Exchange rate constant and [b] population from global fit of relaxation dispersion data of residues with significant relaxation dispersion at all magnetic fields. [c] Residue‐specific chemical shift difference between ground and excited state. Details on the fitting procedure are given in the Supporting Information.