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. 2016 Apr 7;64(5):1774–1784. doi: 10.1002/hep.28526

Figure 1.

Figure 1

(A,B) Activated platelets bind to the endothelium, causing the endothelium to up‐regulate and secrete CXCL8 and CCL2. These chemokines recruit T cells and neutrophils to the endothelium. (C) T cells use the platelets to bind to the endothelium. Platelets use CD44 to bind sinusoidal hyaluronic acid, allowing T cells to survey the liver for viral antigen.