Phylogenetic trees of ST131 strains. ML phylogenetic trees were estimated using PHYML 3.0 and SH statistics for branch support. Antibiotics are abbreviated as follows: A/C, amoxicillin and clavulanate; CMZ, cefmetazole; ST, trimethoprim-sulfamethoxazole; FOM, fosfomycin; LVX, levofloxacin; GM, gentamicin. The countries are shown in parentheses after the strain name and abbreviated as follows: DNK, Denmark; NPL, Nepal; GBR, Great Britain; JPN, Japan; TZA, Tanzania; KOR, South Korea; LBN, Lebanon; AUT, Austria; THA, Thailand. Susceptibility data are available only for the 11 ESBL-E. coli ST131 isolates from the National Center for Global Health and Medicine, Japan, and 54 ESBL-E. coli ST131 isolates from Tribhuvan University, Nepal. For isolates from Japan, ampicillin-sulbactam was used instead of amoxicillin-clavulanate. For resistance genes, a filled square means positive for the resistance gene and an open square means negative for the resistance gene.