Table 2.

Association between retinopathy and quantitative retinal microvascular measures with white matter hyperintensities

Variable	Model 1 OR (95% CI)	P	Model 2 OR (95% CI)	P	Model 3 OR (95% CI)	P
Retinopathy
R0	Reference		Reference		NR
R1	1.14 (0.89, 1.46)	0.3	1.03 (0.79, 1.33)	0.9
R2	5.64 (2.64, 12.09)	<0.001	4.35 (1.98, 9.56)	<0.001
Trend		0.001		0.04
Arteriolar diameter	0.99 (0.97, 1.00)	0.02	0.98 (0.97, 0.99)	0.01	0.98 (0.97, 0.99)	0.002
Number of arterioles	0.91 (0.86, 0.967)	0.002	0.92 (0.87, 0.98)	0.006	0.92 (0.87, 0.98)	0.03
Number of symmetrical arteriolar bifurcations	0.90 (0.83, 0.98)	0.02	0.88 (0.81, 0.97)	0.007	0.88 (0.80, 0.96)	0.006
Arteriolar tortuosity	0.97 (0.92, 1.03)	0.4	0.96 (0.90, 1.02)	0.2	0.96 (0.90, 1.02)	0.2
Log arteriolar optimality deviation	0.98 (0.88, 1.09)	0.7	1.00 (0.90, 1.12)	>0.9	1.01 (0.90, 1.12)	>0.9
Venular diameter	0.99 (0.99, 1.01)	0.9	1.00 (0.99, 1.01)	0.6	1.00 (0.99, 1.01)	0.6
Number of venules	0.94 (0.89, 0.99)	0.03	0.96 (0.90, 1.01)	0.1	0.96 (0.90, 1.01)	0.1
Venular tortuosity	1.14 (1.04, 1.23)	0.003	1.11 (1.01, 1.21)	0.02	1.11 (1.02, 1.21)	0.02
Arteriovenous ratio	0.40 (0.15, 1.04)	0.06	0.32 (0.12, 0.86)	0.02	0.31 (0.12, 0.84)	0.02

Models and abbreviations as for table 1.