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. 2016 Oct 18;6:35277. doi: 10.1038/srep35277

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Copyright © 2016, The Author(s)

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Plasma homoarginine (A) and 6-guanidino-2-oxocaproic acid (GOCA) (B) levels in wild type (wt) and alanine-glyoxylate aminotransferase 2 knock-out (AGXT2 KO) mice. ***P < 0.001 vs wt. mRNA levels of alanine-glyoxylate aminotransferase 2 (Agxt2), L-arginine: glycine amidinotransferase (Agat) and guanidinoacetate N-methyltransferase (Gamt) in the liver (C) and kidney (D) of AGXT2 KO and wt mice. ***P < 0.001; *P < 0.05.