Figure 4. Distribution of non-synonymous (NSY: black), and indels, read-through (RTH) and non-sense (NON) (light gray) mutations in B. microti coding sequences with at least 2 mutations.

Genes carrying R1- specific mutations are indicated with (R), those carrying non-R1specific mutations are indicated with (O), and those genes carrying both R1 and non-R1 specific mutations are labeled with (−). Genes located in chromosome ends are marked with (*). Genes encoding members of the BMN family are marked with (1) to indicate the BMN1 family and (2) for the BMN2 family. Antigens depicted are GPI-anchored protein (G), transmembrane proteins (T) and secreted proteins (S). Genes encoding members of the secretome with non-R1 specific mutations are highlighted in gray.