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. 2016 Oct 18;6:35284. doi: 10.1038/srep35284

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(A) Venn diagram illustrating the composition of the B. microti set of proteins targeted to the mitochondria, apicoplast and the secretome. Identification of the mitochondrial and apicoplast sets of proteins helped curate the main constituents of the secretome, from which the organelle-targeted genes were excluded. (B) Overlap between secretome-encoding genes and genes that either harbor SNPs and indels, are ranked in the top 10 most expressed B. microti genes, or are differentially expressed between isolates. (C) Model of the moving junction core complex of B. microti predicted based on the updated genome annotation.