Table 3.
Regions contributing to the corresponding rCBF pattern with high confidence (|Z| ≥ 1.64, p ≤ 0.05) in AD
| Hemisphere | MNI coordinates | Region | Z score |
|---|---|---|---|
| L | −60, −40, 0 | Middle temporal gyrus | −1.9 |
| R | 68, −32, −16 | Middle temporal gyrus | −1.9 |
| L | −12, −28, 12 | Thalamus | −2.4 |
| R | 16, −28, 12 | Thalamus | −2.3 |
| L | −4, −48, 20 | Posterior cingulate | −2.2 |
| R | 4, −48, 28 | Posterior cingulate | −2.6 |
| L | 0, 20, 28 | Anterior cingulate | −2.2 |
| R | 4, 20, 28 | Anterior cingulate | −2.8 |
| L | 0, −56, 36 | Precuneus | −4.0 |
| R | 4, −60, 32 | Precuneus | −3.9 |
| L | −40, −64, 44 | Inferior parietal | −2.4 |
| R | 48, −64, 44 | Inferior parietal | −2.9 |
| L | −36, 20, 52 | Middle frontal gyrus | −2.1 |
| R | 32, 32, 44 | Middle frontal gyrus | −1.7 |
| L | −24, 28, 52 | Superior frontal gyrus | −2.2 |
| L | −16, 16, −24 | Inferior frontal gyrus | −1.9 |
| L | −16, −64, −36 | Posterior cerebellum | 4.2 |
| R | 24, −64, −36 | Posterior cerebellum | 3.8 |
| L | −16 −64, −28 | Anterior cerebellum | 3.2 |
| R | 24, −64, −28 | Anterior cerebellum | 3.8 |
| L | −20, 16, −8 | Putamen | 2.2 |
| R | 24, 8, −4 | Putamen | 1.7 |
| L | −20, −4, −4 | Pallidum | 2.1 |
| R | 24, −12, 0 | Pallidum | 1.8 |
| L | −56, 0, 24 | Precentral gyrus | 2.2 |
| R | 60, 4, 24 | Precentral gyrus | 1.8 |
| L | −16, 48, 4 | Medial frontal gyrus | 2.5 |
| R | 20, 44, 4 | Medial frontal gyrus | 2.3 |
| L | −20, −56, −12 | Lingual gyrus | 2.0 |
| R | 20, −56, −12 | Lingual gyrus | 2.0 |
Key: AD, Alzheimer's disease; L, left; MNI, Montreal Neurological Institute; R, right; rCBF, regional cerebral blood flow.