Table 2. Absolute number of different T cells populations of multiple sclerosis patients (MS) with or without fingolimod therapy.
| MS patients without fingolimod therapy |
MS patients with fingolimod therapy |
||||||
|---|---|---|---|---|---|---|---|
| without DMD | with IFN-β | relapse-free | relapse-experienced | ||||
| in rem | at rel | in rem | at rel | in rem | at rel | 3 month after rel | |
| No. of patients | 5 | 5 | 11 | 4 | 11 | 4 | 4 |
| Lymphocytes/μl | 1548 ± 378.1 | 1284 ± 424.0 | 1437 ± 534.7 | 1795 ± 335.2 | 433.6 ± 196.9 | 425 ± 152.3 | 455 ± 151.7 |
| T cells/μl | |||||||
| Total | 1281 ± 386 | 964.3 ± 312.9 | 1134.9 ± 431.4 | 1377.6 ± 344.6 | 162.8 ± 155.8 | 122.7 ± 45.9 | 117.7 ± 83.3 |
| CD56+cells/μl | |||||||
| CD3+ | 43.9 ± 24.0 | 16.6 ± 11.0 | 29.4 ± 34.0 | 14.7 ± 14.0 | 20.1 ± 23.0 | 71.1 ± 36.0 | 56.9 ± 43.9 |
| CD4+ | 8.7 ± 4.0 | 6.3 ± 3.0 | 3.9 ± 2.0 | 6.3 ± 7.0 | 2.8 ± 3.0 | 10.9 ± 13.0 | 11.1 ± 11.6 |
| CD8+ | 24.2 ± 15.0 | 8.8 ± 7.0 | 21.2 ± 27.0 | 8.1 ± 7.0 | 10.5 ± 15.0 | 40.8 ± 15.0 | 23.5 ± 10.3 |
Mean values (± standard deviation) are reported.
Abbreviations are as follows, without DMD: without disease-modifying drug, with IFN-β: with interferon β therapy, rem: remission, rel: relapse.