Fig. 3.

Scatter plot illustrating distribution of the fold change for the expression of 3 major histocompatibility complex genes in sporadic inclusion body myositis groups compared with controls as determined by real-time quantitative polymerase chain reaction. All expression levels were normalized to the expression of the reference gene, PPIA, and relative to the mean normalized expression of all the controls. The solid black lines denote the medians. Only significant Mann-Whitney U test p values (<0.05) regarding comparisons of patient groups with controls are shown. Abbreviations: CD74, CD74 molecule, major histocompatibility complex, class II invariant chain; HLA-A, major histocompatibility complex, class I, A; HLA-DRA, major histocompatibility complex, class II, DR alpha.