Table 3. Weighted Genetic Risk Scores from GWAS SNPs and their associations with BMI in Sample A.
n | Effect on BMI per additional risk allele [CI 95%] | p-value* | E. Var (%) | |
---|---|---|---|---|
SNP group#1 | ||||
All population | 881 | 0.16 [0.11–0.23] | p<0.008 | 1.46 |
Age [18–54] years | 444 | 0.10 [0.01–0.17] | 0.08 | 0.56 |
Age > 54 years | 437 | 0.23 [0.14–0.32] | p<0.008 | 2.74 |
SNP group#2 | ||||
All population | 854 | 0.11 [0.08–0.15] | p<0.008 | 2.08 |
Age [18–54] years | 452 | 0.08 [0.03–0.13] | p<0.008 | 1.10 |
Age > 54 years | 426 | 0.13 [0.07–0.19] | p<0.008 | 2.90 |
E. Var: Explained Variability
CI: Confidence Interval
SNP: Single Nucleotide Polymorphism
BMI: Body Mass Index
* p-value corrected by multiple test