Table 4. Weighted Genetic Risk Scores from GWAS SNPs and their associations with BMI in Sample B.
n | Effect on BMI per additional risk allele [CI 95%] | p-value | E. Var (%) | |
---|---|---|---|---|
SNP group#1 | ||||
All population | 124 | 0.20 [0.07–0.35] | 0.02 | 2.40 |
Men | 82 | 0.14 [-0.01–0.31] | 0.05* | n.c |
Women | 61 | 0.28 [-0.05–0.63] | 0.05 | n.c |
SNP group#2 | ||||
All population | 117 | 0.02 [-0.08–0.11] | 0.28 | n.c |
Men | 69 | -0.03 [-0.18–0.07] | 0.33 | n.c |
Women | 53 | 0.04 [-0.16–0.25] | 0.34 | n.c |
E. Var: Explained Variability
CI: Confidence Interval
BMI: Body Mass Index
SNP: Single Nucleotide Polymorphism
n.c: not calculated because of non significant association and/or low sample size
* values obtained with 100 bootstraps