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. 2016 Oct 27;11(10):e0164443. doi: 10.1371/journal.pone.0164443

Table 5. Comparison of genetic versus non-genetic model for 10% weight gain prediction at one year after transplantation.

AUROC [95% CI] Specificity Sensitivity Accuracy LRT-p IDI [95% CI]* NNG
Sample A SNP group#1
non genetic model 0.66 [0.58–0.72] 0.59 0.66 0.61 0.0004 0.08 [0.06–0.10] 24
genetic model 0.74 [0.70–0.83] 0.61 0.77 0.65
SNP group#2
non genetic model 0.66 [0.54–0.69] 0.65 0.62 0.64 0.008 0.17 [0.14–0.20] 13
genetic model 0.80 [0.71–0.84] 0.70 0.77 0.72
Sample B SNP group#1
non genetic model 0.67 [0.61–0.88] 0.55 0.76 0.63 0.04 0.36 [0.28–0.45] 6
genetic model 0.89 [0.79–0.97] 0.78 0.88 0.81

AUROC: Area Under the Receiver Operating Characteristic Curve

IDI: Integrated Discrimination Improvement

NNG: Number Needed to Genotype

LRT: Likelihood Ratio tests

SNP: Single Nucleotide Polymorphism

CI: Confidence Interval

*p-value < 0.01