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. 2016 Oct 27;11(10):e0165422. doi: 10.1371/journal.pone.0165422

Table 1. Potencies (log ED50) of selepressin, arginine vasopressin (AVP), and norepinephrine (NE) for hemodynamic parameters in non-atherosclerotic (NA) and atherosclerotic (A) rabbits.

HemodynamicParameter Log ED50 (log(ng.kg-1.min-1))
Selepressin AVP NE
NA A NA A NA A
DAP −7.4±0.2 −8.5±0.9 −10.0±7.5 −8.7±1.1 −6.0±0.3 −5.8±0.4
MAP −7.2±0.3 −8.5±1.3 No fit −8.6±1.4 −6.1±0.3 −5.7±0.3
SAP −7.2±0.4 No fit −6.6±1.9 −8.6±3.2 −6.1±0.2 −5.±0.2
HR −7.6±0.3 −7.4±0.2 −8.6±0.2 −8.5±0.5 −6.9±0.9 −7.0 ±1.2
ABF −8.7±0.7 −8.1±1.2 −8.1±0.5 −8.4±0.2 −6.5±0.4 −6.2±0.7
SV −4.9±6.2 −6.5±1.0 −7.5±5.9 −7.9±5.1 −6.5±0.4 −5.4±0.4

All values are mean ± standard error of the mean. Selepressin and AVP were statistically compared for hemodynamic effects by means of comparison of fits (extra-sum-of-squares F test). No fit: dose-response curve could not be statistically fitted. See legend of Fig 2 for the hemodynamic parameter abbreviations.