Table 1. Plasma clinical biochemistry in BSO-treated mice after 8 weeks1.
| Control (N = 23) | BSO (N = 20) | BSO/Control 2 (%) | |
|---|---|---|---|
| Glucose, mmol/L | 11.3 (10.1, 12.3) | 10.1 (8.08, 13.1) | 89 |
| Triglycerides, mmol/L | 2.84 (2.51, 3.09) | 1.78 (1.26, 1.91) | 63** |
| Total cholesterol, mmol/L | 5.1 (4.79, 5.44) | 5.05 (4.68, 5.36) | 99 |
| LDL-cholesterol, mmol/L | 0.99 (0.93, 1.06) | 0.94 (0.86, 1.05) | 95 |
| HDL-cholesterol, mmol/L | 3.51 (3.29, 3.73) | 3.61 (3.44, 3.83) | 103 |
| Albumin, g/L | 26.8 (26.4, 27.7) | 24.4 (23.7, 25.5) | 91** |
| Total protein, g/L | 52.8 (52.0, 54.3) | 48.7 (48.0, 50.6) | 92** |
| ALT, U/L | 34 (28, 42) | 22 (18.5, 27.5) | 65** |
| Creatinine, μmol/L | 10.2 (9.7, 11.7) | 8.9 (8.3, 9.4) | 87** |
1. Data represents median (25%, 75%). Parameters were measured after an overnight fast.
**P<0.001, Mann Whitney U test.
ALT, alanine aminotransferase.
2. Calculated using medians.