Fig 3. IND02 and IND02-trimer inhibition of gp120 binding to immobilized HS.

HIV-1 gp120 (MN) was injected over the immobilized HS surface at 10 μl/min in the presence or absence of IND02 (A) or IND02-trimer (B) at the indicated concentrations (in μM). The specific binding responses in resonance unit (RU) was recorded as a function of time (s), and after each injection the surface was regenerated by a short pulse of 0.05% SDS and 2M NaCl.