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The Fig describes the synthesis of 1-InsP7, 5-InsP7 and 1,5-InsP8 in both yeasts and mammalian cells. IP6K1/2/3 = isoforms 1, 2 and 3 of inositol hexakisphosphate kinase (Kcs1 is the single yeast isoform); PPIP5K1/2 = isoforms 1 and 2 of diphosphoinositol pentakisphosphate kinase (Asp1 and Vip1 are the single isoforms in Schizosaccharomyces pombe and Saccharomyces cerevisiae, respectively).
