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. 2016 Oct 27;11(10):e0165327. doi: 10.1371/journal.pone.0165327

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© 2016 Yang et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — In CGI analysis, every CGI was divided into 20 bin for evaluating the methylation level. (A) Distribution of CGI sites in different gene elements. (B) Different methylation levels of cytosine (percentage) between prepubertal and pubertal stages. Prepub = prepuberty; Pub = puberty; CGI = CpG island.