Table 2. Kidney function and calciotropic and phosphaturic hormones before and at different time points after left ventricular assist device implantation.
| Parameter | t0 | t1 | t2 | t3 | t4 | P-value |
|---|---|---|---|---|---|---|
| n = 69 | n = 51 | n = 62 | n = 47 | n = 35 | ||
| eGFR (ml/min/1.73m2) | 56 (39;82) | 82 (54;122)** | 86.5 (57;107)*** | 72 (41;100) | 58 (35;81) | <0.001 |
| 25OHD (ng/ml) | 11.8 (8.9;17.9) | 11.3 (8.5;16.8) | 10.9 (8.0;14.7) | 11.1 (8.3;14.6) | 11.1 (8.3;14.6) | 0.564 |
| PTH (pg/ml) | 42 (32;95) | 68 (37;107) | 48 (24;77) | 52 (37;84) | 52 (37;83) | 0.179 |
| 1,25(OH)2D (pg/ml) | 7.7 (4.9;13.7) | 7.8 (4.9;11.4) | 8.3 (4.9;15.5) | 12.1 (6.1;21.6)* | 12.1 (6.1;21.6)* | 0.024 |
| FGF-23 (RU/ml) | 683 (298;2356) | 964 (521;2023) | 417 (294;984)* | 438 (281;1106)** | 535 (334;1506) | 0.008 |
Data are expressed as median and interquartile range. Abbreviations: eGFR, estimated glomerular filtration rate; 25OHD, 25-hydroxyvitamin D, PTH, parathyroid hormone; 1,25(OH)2D, 1,25-dihydroxyvitamin D; FGF-23, fibroblast growth factor-23; t0, before assist device implantation; t1,12 days post-intervention; t2, 30 days post-intervention; t3, 83 days post-intervention; t4, 300 days post-intervention *,**,*** significant different vs. t0, *P<0.05;**P<0.01;***P<0.001