Table 2. Odds of Case Probands Mating, Relative to Matched Population Probands, by Diagnosis and Gender.
All Women |
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Total Proband, No. |
Proportion Mated |
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Proband Diagnosis | Case | Matched Population |
Case, No. | % | Matched Population, No. |
% | ORa | (95% CI) |
ADHD | 19 502 | 97 510 | 6167 | 31.6 | 31 775 | 32.6 | 0.96 | (0.94-0.98) |
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ASD | 8044 | 40 220 | 975 | 12.1 | 11 056 | 27.5 | 0.36 | (0.34-0.39) |
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Schizophrenia | 33 562 | 167 810 | 17 236 | 51.4 | 140 203 | 83.6 | 0.21 | (0.20-0.21) |
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Bipolar | 46 381 | 231 905 | 33 977 | 73.3 | 186 325 | 80.4 | 0.67 | (0.66-0.68) |
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Depression | 212 670 | 1 063 350 | 156 683 | 73.7 | 796 813 | 74.9 | 0.93 | (0.93-0.94) |
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GAD | 18 540 | 92 700 | 13 280 | 71.6 | 68 477 | 73.9 | 0.89 | (0.87-0.92) |
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Agoraphobia | 5720 | 28 600 | 3849 | 67.3 | 19 603 | 68.5 | 0.94 | (0.90-0.99) |
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Social phobia | 9250 | 46 250 | 4790 | 51.8 | 26 629 | 57.6 | 0.79 | (0.76-0.82) |
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OCD | 11 319 | 56 595 | 5249 | 46.4 | 31 289 | 55.3 | 0.70 | (0.68-0.72) |
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Substance | 117 870 | 589 350 | 81 815 | 69.4 | 418 505 | 71.0 | 0.93 | (0.92-0.94) |
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Anorexia | 13 976 | 69 880 | 5018 | 35.9 | 30 967 | 44.3 | 0.70 | (0.68-0.73) |
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Tics | 1125 | 5625 | 339 | 30.1 | 2034 | 36.2 | 0.76 | (0.69-0.84) |
Abbreviations: ADHD, attention-deficit/hyperactivity disorder; ASD, autism spectrum disorder; GAD, generalized anxiety disorder; OCD, obsessive compulsive disorder; OR, odds ratio.
P value < .001.