TABLE I.
Parameter values of the BD-kMC simulation.
Quantity | Parameter | Value | Notes |
---|---|---|---|
kBT | Thermal energy | 4.11 ×10−21 J | Room temperature |
l | MT length | 250 nm | Chosen |
b | MT diameter | 25 nm | Ref. [61] |
ϵ | Energy scale of the WCA potential | kBT | Refs. [55–57] |
η | Fluid viscosity | 1.0 Pa s | Cytoplasmic viscosity, Ref. [62] |
ρ | Linear density of motor binding sites along MT | — | Appears only in dimensionless concentration |
μ m | Motor chemical potential | — | Appears only in dimensionless concentration |
u 0 | Motor binding free energy | — | Appears only in dimensionless concentration |
vw | Motor speed (zero force) | Reference 4.5 μm/s, range 0.14–18 μm/s | Of order 1 μm/s, Ref. [50] |
k 0 | Unbinding rate of motors | 28.1 s−1 | Processivity of 160 nm, Ref. [63] |
fs | Stall force | 1 pN | Ref. [50] |
K | Motor spring constant | 0.013 pN/nm | Decreased from Ref. [64] to give appropriate range of motor-mediated interaction for zero-equilibrium-length springs |