Figure 1. The mtHEPOR fetuses are polycythemic and wtHEPOR fetuses are anemic compared to mEpoR fetuses at mid- to late-gestation (E12.5~E16.5). These phenotypes transiently disappear around perinatal period, and then reappear at 3 weeks after birth.
M, wtH, mtH denote mEpoR, wtHEPOR, and mtHEPOR genotypes, respectively. * and ** denote P<0.05 and P<0.001 for mEpoR versus wtHEPOR, and mtHEPOR, respectively. The mean and standard error of hematocrit levels from at least 10 embryos/neonatal pups for each time-point are shown.