| Candidates identified by SILAC in three biological replicates (adjusted p < 0.05) |
|
|
|
|
|
|
|
|
| TFF1
|
TFF1 |
P04155 |
Trefoil factor 1 |
+ |
4.5 |
6.6 |
Yes |
Primary |
| MCM6
|
MCM6 |
Q14566 |
DNA replication licensing factor MCM6 |
+ |
1.5 |
2.7 |
Yes |
Primary |
| KPNA2
|
IMA1 |
P52292 |
Importin subunit alpha-1 |
+ |
3.1 |
2.5 |
Yes |
Primary |
| TST
|
THTR |
Q16762 |
Thiosulfate sulfurtransferase |
+ |
1.7 |
1.9 |
Yes |
Primary |
| BCL2L11
|
B2L11 |
O43521 |
Bcl-2-like protein 11 |
+ |
1.5 |
1.7 |
Yes |
Primary |
| ASNS
|
ASNS |
P08243 |
Asparagine synthetase [glutamine-hydrolyzing] |
+ |
1.7 |
1.5 |
Yes |
Primary |
| CDK2
|
CDK2 |
P24941 |
Cyclin-dependent kinase 2 |
+ |
1.6 |
1.4 |
Yes |
Primary |
| RAB31
|
RAB31 |
Q13636 |
Ras-related protein Rab-31 |
+ |
1.5 |
1.3 |
Weak |
Transient |
| TPM1
|
TPM1 |
P09493–3 |
Isoform 3 of Tropomyosin alpha-1 chain |
+ |
1.7 |
1.1 |
Weak |
Transient |
| DNAJA1
|
DNJA1 |
P31689 |
DnaJ homolog subfamily A member 1 |
+ |
1.7 |
1.1 |
Weak |
Transient |
| DUT
|
DUT |
P33316 |
Deoxyuridine 5Ȳ-triphosphate nucleotidohydrolase |
− |
1.8 |
3.5 |
Yes |
Secondary |
| CDK1
|
CDK1 |
P06493 |
Cyclin-dependent kinase 1 |
− |
n/a |
2.8 |
Yes |
Secondary |
| NAB2
|
NAB2 |
Q15742 |
NGFI-A-binding protein 2 |
− |
1.8 |
1.9 |
Yes |
Secondary |
| TOP2A
|
TOP2A |
P11388 |
DNA topoisomerase 2-alpha |
− |
3.7 |
1.5 |
Yes |
Secondary |
| HSP90AB1* |
HS90B |
P08238 |
Heat shock protein HSP 90-beta |
− |
1.7 |
1.3 |
Yes |
Secondary |
| ESR1
|
ESR1 |
P03372 |
Estrogen receptor |
− |
0.4 |
0.7 |
Yes |
Secondary |
| LXN
|
LXN |
Q9BS40 |
Latexin |
− |
1.5 |
0.5 |
Yes |
Secondary |
| SLC9A3R1
|
NHRF1 |
O14745 |
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 |
− |
1.6 |
1.3 |
No |
Indirect |
| ACACA
|
ACACA |
Q13085 |
Acetyl-CoA carboxylase 1 |
− |
1.5 |
0.9 |
Weak |
False |
| Controls for hypoxia |
|
|
|
|
|
|
|
|
| SLC2A1
|
GTR1 |
P11166 |
Solute carrier family 2, facilitated glucose transporter member 1 |
+ |
1.4 |
1.8 |
Weak |
|
| ALDOA
|
ALDOA |
P04075 |
Fructose-bisphosphate aldolase A |
23 |
1.1 |
1.1 |
No |
|
| ALDOC
|
ALDOC |
P09972 |
Fructose-bisphosphate aldolase C |
23 |
1.2 |
1.2 |
No |
|
| Housekeeping proteins used for normalization of SRM data |
|
|
|
|
|
|
|
|
| ACTB
|
ACTB |
P60709 |
Actin, cytoplasmic 1 |
+ |
1.0 |
1.0 |
No |
|
| CS
|
CISY |
O75390 |
Citrate synthase, mitochondrial |
+ |
1.1 |
1.0 |
No |
|
| IDH2
|
IDHP |
P48735 |
Isocitrate dehydrogenase [NADP], mitochondrial |
+ |
1.0 |
1.1 |
No |
|
| TALDO1
|
TALDO |
P37837 |
Transaldolase |
+ |
0.9 |
1.1 |
No |
|
| ENO1
|
ENOA |
P06733 |
Alpha-enolase |
− |
0.9 |
0.8 |
No |
|
| GAPDH
|
G3P |
P04406 |
Glyceraldehyde-3-phosphate dehydrogenase |
− |
1.1 |
0.9 |
No |
|
| PKM
|
KPYM |
P14618 |
Pyruvate kinase PKM |
− |
1.2 |
1.0 |
No |
|
| PKM/PKLR
|
KPYM/KPYR |
P14618/P30613
|
Pyruvate kinase PKM/Pyruvate kinase PKLR |
− |
1.2 |
1.0 |
No |
|
| RPL27A
|
RL27A |
P46776 |
60S ribosomal protein L27a |
− |
1.1 |
1.1 |
No |
|
| RPL30
|
RL30 |
P62888 |
60S ribosomal protein L30 |
− |
0.9 |
1.2 |
Weak |
|
| RPS3
|
RS3 |
P23396 |
40S ribosomal protein S3 |
− |
1.2 |
1.1 |
No |
|
| TUBB
|
TBB5 |
P07437 |
Tubulin beta chain |
− |
1.2 |
1.2 |
Weak |
|
| UBB
|
UB |
P0CG47 |
Polyubiquitin-B |
− |
1.0 |
1.1 |
No |
|
