Table 2a.

Continuous, longitudinal association between age and grip strength, adjusted for HIV serostatus and other confounding variables, from October 1, 2007 – September 30, 2014 (N = 1,552)

Dependent Variable: Grip strength (kg) Independent variables:	Coefficient	S.E.	p-value
Age (per year centered at 50 years)	−0.330	.065	< 0.001
Age squared	−0.005	.002	< 0.01
HIV infection	0.293	.467	0.53
HIV * Age	− 0.093	.034	0.01
Body Mass Index (kg/m2)	0.121	.028	< 0.001
Non-White Racea	−1.440	.458	< 0.01
College educationb	1.818	.412	< 0.001
Kidney diseasec	−0.351	.121	< 0.01
Peripheral Neuropathyd	−0.230	.126	0.07

Table 2 shows the final longitudinal model assessing the associations among age, HIV, and grip strength decline. Smoking, history of drug and alcohol use, liver disease, hypertension, arthritis, mental quality of life, hepatitis B, and hepatitis C were not significant and were not included in the final model.

^aBlack (non-Hispanic), Black Hispanic, American Indian or Alaskan Native, Asian or Pacific Islander, other Hispanic, or other

^bCompleted college degree or more

^cEstimated Glomerular Filtration Rate < 60 or Urine Protein to Creatinine Ratio ≥ 200

^dCurrent or past report of pain, burning, numbness, or pins and needles sensation in the feet or legs, or measured inability to detect vibratory sensation in either foot