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Lymphatic pump dysfunction in MLVs isolated from MetSyn rats. A) Representative diameter traces over a 1 minute period of control and MetSyn MLVs at each pressure tested. Contraction frequency (B) and ejection fraction (C) for control and MetSyn MLVs. D) Calculated output, fractional pump flow, was significantly lower at all 3 pressures tested. Data are presented as Mean ± SEM. n=8; * denotes significance at p<0.05; ˆ denotes significance at p<0.10.
