Table 1.
Demographic and HIV disease characteristics for monoinfection and dual infection groups.
| Monoinfection (N = 29) | Dual infection (N = 9) | p value | |
|---|---|---|---|
| Age, median (IQR) | 50 (45-53) | 52 (48-55) | 0.63 |
| Sex, No. (%) | 0.57 | ||
| Female | 3 (10) | 2 (22) | |
| Male | 26 (90) | 7 (78) | |
| Ethnicity, No. (%) | 0.47 | ||
| Non-Hispanic Black | 14 (48) | 3 (33) | |
| Non-Hispanic White | 13 (45) | 4 (44) | |
| Hispanic | 2 (7) | 2 (22) | |
| Education years, median (IQR) | 14 (12-15) | 13 (12-16) | 0.76 |
| Neurocognitive Comorbidity, No. (%) | 0.088 | ||
| Contributing | 6 (21) | 5 (56) | |
| Incidental | 23 (79) | 4 (44) | |
| Hepatitis C status, No. (%) | 1.00 | ||
| Negative | 23 (79) | 7 (78) | |
| Positive | 6 (21) | 2 (22) | |
| Estimated duration of infection (years), median (IQR) | 10.3 (5.6-14.2) | 15.5 (6.7-17.1) | 0.22 |
| Current CD4 T-cell count, median cells/μL (IQR) | 464 (327-671) | 513 (381-853) | 0.32 |
| Nadir CD4 T-cell count, median cells/μL (IQR) | 108 (15-243) | 133 (86-170) | 0.70 |
| Plasma viral load, median log10 copies/mL (IQR) | <1.7 (1.7-2.81) | <1.7 (1.7-2.07) | 0.57 |
| Detectable plasma viral load, N (%) | 0.48 | ||
| Undetectable | 15 (52) | 6 (67) | |
| Detectable | 14 (48) | 3 (33) | |
| CSF viral load, median log10 copies/mL (IQR) | <1.7 (1.7-1.7) | <1.7 (1.7-1.7) | 0.32 |
| Detectable CSF viral load, N (%) | 0.55 | ||
| Undetectable | 21 (88) | 8 (100) | |
| Detectable | 3 (12) | 0 (0) | |
| Sexually transmitted infections, No. (%)* | 0.55 | ||
| Yes | 4 (14) | 0 ( 0) | |
| No | 25 (86) | 9 (100) | |
| Overall risk factor for HIV infection, No. (%) | 0.051 | ||
| Sexual exposures | 29 (100) | 7 (78) | |
| IVDU | 0 (0) | 2 (22) | |
*
Sexually transmitted infections included syphilis, gonorrhea, chlamydia, and herpes simplex.
IQR: interquartile range; CSF: cerebrospinal fluid; MSM: men who have sex with men; IVDU: intravenous drug use.