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The effect of impaired kisspeptin signalling on neuropeptide Y (Npy) and pro-opiomelanocortin (Pomc) hypothalamic gene expression in 8 week (wk) gonad intact (A, B) and gonadectomised (GNX) (C, D) mice. As indicated, * p<0.05 compared to wild type (WT – shown as white bars, Kiss1r KO – black bars). Values are the mean ± SEM. n=3–9 per group (n=3 in the intact female KO group only).
