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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: J Thromb Haemost. 2016 Aug 17;14(10):1978–1987. doi: 10.1111/jth.13411

Table 3.

Incidence rates (IR) per 1000 person-years and hazard ratios (HR) with 95% confidence intervals (CI) of work-related disability (official date of disability pension) after venous thromboembolism (VTE).

Person-years Work-related disability Crude IR (95% CI) Model 1 HR (95% CI) Model 2 HR (95% CI) Model 3 HR (95% CI) Model 4 HR (95% CI)
Venous thromboembolism (VTE )
No VTE 711337 9610 13.5 (13.2–13.7) 1 (reference) 1 (reference) 1 (reference) 1 (reference)
VTE 1918 72 37.5 (29.7–47.3) 1.62 (1.29–2.04) 1.57 (1.24–1.98) 1.44 (1.12–1.85) 1.30 (1.01–1.67)

Deep vein thrombosis (DVT)

No DVT 712028 9630 13.5 (13.2–13.8) 1 (reference) 1 (reference) 1 (reference) 1 (reference)
DVT 1227 52 42.4 (32.3–55.6) 1.80 (1.37–2.36) 1.77 (1.35–2.33) 1.66 (1.23–2.23) 1.44 (1.07–1.94)

Pulmonary embolism (PE)

No PE 712565 9662 13.6 (13.3–13.8) 1 (reference) 1 (reference) 1 (reference) 1 (reference)
PE 691 20 28.9 (18.7–44.9) 1.28 (0.83–1.99) 1.19 (0.76–1.87) 1.06 (0.66–1.72) 1.04 (0.64–1.67)

Unprovoked VTE

No unprovoked VTE 712321 9646 13.5 (13.3–13.8) 1 (reference) 1 (reference) 1 (reference) 1 (reference)
Unprovoked VTE 935 36 38.5 (27.8–53.4) 1.52 (1.09–2.11) 1.48 (1.06–2.07) 1.40 (0.97–2.02) 1.34 (0.93–1.94)

Provoked VTE

No provoked VTE 712272 9646 13.5 (13.3–13.8) 1 (reference) 1 (reference) 1 (reference) 1 (reference)
Provoked VTE 983 36 36.6 (26.4–50.7) 1.73(1.25–2.40) 1.66 (1.19–2.30) 1.47 (1.04–2.08) 1.26 (0.89–1.78)

Model 1: Adjusted for age and sex

Model 2: adjusted for age, sex, BMI, smoking, education level and marital status

Model 3: adjusted for age, sex, BMI, smoking, education level, marital status, history of cancer, diabetes and cardiovascular disease

Model 4: Model 3 + self-rated general health