Table 2.
Frequency of meniscal damage and surgery status at enrollment and 1 year prior to the case-defining visit and outcome (incident radiographic osteoarthritis and cartilage loss)
| Outcome (incident ROA / cartilage loss) | No incident ROA (%) | Incident ROA (%) | No cartilage loss – medial (%) | Any cartilage loss – medial (%) | No cartilage loss – lateral (%) | Any cartilage loss – lateral (%) |
|---|---|---|---|---|---|---|
| Meniscal status at OAI enrolment (BL) | ||||||
| --- (N = 708) --- | --- (N = 663 with cartilage loss data) --- | |||||
|
| ||||||
| Normal or intrameniscal signal at BLa | 243 (68.5) | 209 (59.0) | 325 (63.9) | 95 (61.7) | 378 (65.0) | 44 (51.2) |
| Tear at BLb | 92 (26.0) | 129 (36.4) | 157 (30.8) | 54 (35.1) | 174 (29.9) | 37 (43.0) |
| Meniscal maceration at BLc | 19 (5.4) | 16 (4.5) | 27 (5.3) | 5 (3.3) | 30 (5.2) | 5 (5.8) |
|
| ||||||
| Meniscal status at 1 year prior to case-defining visit (P-1) | ||||||
| --- (N = 683) --- | --- (N = 663 with cartilage loss data) --- | |||||
|
| ||||||
| Normal or intrameniscal signal at P-1a | 239 (67.5) | 164 (49.9) | 309 (60.7) | 83 (53.9) | 354 (60.8) | 38 (46.9) |
| Tear at P-1b | 95 (26.8) | 143 (43.5) | 164 (32.2) | 65 (42.2) | 192 (33.0) | 37 (45.7) |
| Meniscal maceration at P-1c | 20 (5.7) | 22 (6.7) | 36 (7.1) | 6(3.9) | 36 (6.2) | 6 (7.4) |
|
| ||||||
| Meniscal surgery between P-1 and P0 | 0 (0.0) | 31 (8.8) | 8 (1.6) | 18 (11.7) | 22 (3.8) | 4 (4.7) |
a
MOAKS grades 0 and 1
b
MOAKS grades 2–5
c
MOAKS grades 6–8 (but only grade 6 observed)
ROA radiographic osteoarthritis, BL baseline, P-1 annual visit 1 year prior to case-defining visit, P0 annual visit at the time point when incident ROA was diagnosed (i.e., the case-defining visit)