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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Eur Radiol. 2016 Apr 27;27(1):404–413. doi: 10.1007/s00330-016-4361-z

Table 5.

Cartilage worsening in whole knee (medial and lateral compartments), knees developing radiographic osteoarthritis only

Meniscal status at P-1 or surgery case No cartilage worsening N (%) Cartilage worsening N (%) Adjusted odds of cartilage loss (outcome) Crude odds ratio (95% CI)a Adjusted odds of cartilage loss (outcome) Crude odds ratio (95% CI)b
N = 147 N = 162
No surgery / no meniscal damage 74 (50.3%) 67 (41.4%) Reference Reference
No surgery, but presence of meniscal damage (tear or maceration) 68 (46.2%) 74 (45.7%) 0.98 (0.58,1.67) 0.88 (0.51,1.51)

Meniscal surgeryc 5 (3.4%) 21 (13.0) 4.76 (1.63,13.90)* 4.51 (1.53,13.33)*
a

Logistic regression adjusted for matching criteria (radiographic OA severity defined by Kellgren-Lawrence grade of index and contralateral knee, age, gender) and BMI

b

Logistic regression adjusted for matching criteria (radiographic OA severity defined by Kellgren-Lawrence grade of index and contralateral knee, age, gender), BMI and prevalent MRI features (cartilage damage, effusion, synovitis, BMLs)

c

No data for five knees at P-1

CI confidence interval, BMI body mass index, P-1 annual visit 1 year prior to case-defining visit, BMLs bone marrow lesions