Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Response to 2DG and insulin challenge.
(A) In response to insulin, circulating glucose levels drop more in Magel2 mice (main effect of genotype p < 0.01) and after SG (main effect of surgery p < 0.01). (B) 4 hours after injection, Magel2 mice fail to increase their feeding in response to 2DG, and look similar to saline injected Magel2 mice (genotype × drug effect, ***p < 0.001). Values graphed as mean ± SEM.
