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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Exp Eye Res. 2016 Apr 27;158:73–84. doi: 10.1016/j.exer.2016.04.023

Fig. 4. Examples of gene therapeutic IOP lowering.

Fig. 4

Prostaglandin pathway transduction shows a long-term IOP reduction after a single vector bolus in the cat (A (Barraza et al., 2010)). Inducible cytoablative vector causes a rapid TM cell loss followed by a recovery of IOP and TM cell numbers (Zhang et al., 2014) in this model of TM regeneration (B).