Table 4.
Multinomial logistic regression for wheeze phenotypes stratified by sex (vs. never/infrequent wheeze)*
| Early transient wheeze | Persistent wheeze | |||
|---|---|---|---|---|
| Girls | Boys | Girls | Boys | |
| n=64 | n=101 | n=69 | n=101 | |
| Maternal asthma | 2.03 (0.97, 4.25) | 3.59 (1.90, 6.75) | 2.13 (1.04, 4.35) | 2.21 (1.11, 4.40) |
| Paternal asthma* | 1.29 (0.59, 2.83) | 0.85 (0.35, 2.09) | 1.46 (0.68, 3.15) | 4.27 (2.33, 7.83) |
| Household income >$70,000/year | 0.78 (0.42, 1.46) | 0.85 (0.48, 1.50) | 0.72 (0.38, 1.36) | 0.72 (0.41, 1.26) |
| Child race/ethnicity, vs. white | ||||
| Black* | 0.56 (0.21, 1.53) | 1.25 (0.57, 2.76) | 3.23 (1.55, 6.75) | 1.50 (0.73, 3.09) |
| Hispanic | 0.69 (0.13, 3.59) | 1.11 (0.35, 3.53) | 3.60 (1.06,12.17) | 1.38 (0.47, 4.08) |
| Other | 0.83 (0.38, 1.82) | 1.27 (0.64, 2.51) | 1.39 (0.63, 3.11) | 0.96 (0.46, 2.01) |
| Season of birth, vs. winter | ||||
| Spring | 0.93 (0.46, 1.88) | 1.74 (0.88, 3.43) | 0.98 (0.46, 2.09) | 0.87 (0.45, 1.69) |
| Summer | 0.54 (0.25, 1.19) | 1.36 (0.69, 2.70) | 0.85 (0.40, 1.84) | 0.82 (0.43, 1.57) |
| Fall | 0.52 (0.23, 1.19) | 1.30 (0.63, 2.70) | 0.67 (0.30, 1.52) | 0.86 (0.44, 1.70) |
| Gestation length, weeks | 0.93 (0.81, 1.07) | 1.05 (0.91, 1.21) | 0.97 (0.84, 1.12) | 0.92 (0.81, 1.04) |
| Birthweight for gestational age, z-score* | 0.76 (0.55, 1.03) | 1.13 (0.87, 1.47) | 0.83 (0.61, 1.13) | 1.11 (0.86, 1.42) |
| Duration of breastfeeding, months | 0.92 (0.86, 0.98) | 0.98 (0.92, 1.03) | 0.97 (0.91, 1.03) | 1.02 (0.97, 1.08) |
| Environmental smoke exposure before 1 year | 1.73 (0.67, 4.44) | 1.02 (0.39, 2.64) | 1.96 (0.81, 4.73) | 2.16 (0.96, 4.89) |
| Bronchiolitis before age 1 year | 4.84 (2.34, 9.98) | 10.17 (5.47,18.93) | 4.38 (2.03, 9.45) | 6.49 (3.29,12.79) |
| Atopic dermatitis before age 1 year | 2.06 (1.04, 4.09) | 1.24 (0.69, 2.23) | 2.88 (1.54, 5.38) | 2.01 (1.16, 3.49) |
Statistically significant interaction with sex on persistent wheeze.