Table 2. Unadjusted and adjusted odds ratios for the associations between selected covariates and cataracts.
Parameter | Unadjusted | Multi-adjusteda | ||||
OR | 95% CI | P value | OR | 95% CI | P value | |
Male | 0.55 | 0.44–0.67 | 0.000 | 0.46 | 0.32–0.66 | 0.000 |
Ethnic Han | 2.42 | 1.14–5.14 | 0.022 | 1.62 | 0.7–3.74 | 0.261 |
Age, years | ||||||
<65 | 1.00 | Reference | 1.00 | Reference | ||
65–69 | 1.94 | 1.40–2.68 | 0.000 | 2.22 | 1.53–3.21 | 0.000 |
70–74 | 2.78 | 1.99–3.88 | 0.000 | 3.81 | 2.57–5.65 | 0.000 |
75–79 | 3.26 | 2.34–4.55 | 0.000 | 5.57 | 3.71–8.36 | 0.000 |
80–84 | 3.39 | 2.36–4.89 | 0.000 | 4.85 | 3.02–7.79 | 0.000 |
≥85 | 3.49 | 2.22–5.49 | 0.000 | 5.24 | 2.94–9.32 | 0.000 |
BMI, kg/m2 | ||||||
18.5–24.99 | 1.00 | Reference | 1.00 | Reference | ||
<18.50 | 1.42 | 0.97–2.09 | 0.072 | 1.37 | 0.90–2.08 | 0.142 |
>24.99 | 1.32 | 1.06–1.64 | 0.015 | 1.34 | 1.03–1.74 | 0.031 |
Education | ||||||
Illiterate or semiliterate | 1.00 | Reference | 1.00 | Reference | ||
Primary school | 1.22 | 0.99–1.50 | 0.058 | 1.57 | 1.2–2.05 | 0.001 |
Junior high school | 1.17 | 0.77–1.78 | 0.460 | 1.97 | 1.18–3.28 | 0.009 |
High school graduation or higher | 1.41 | 0.61–3.25 | 0.421 | 2.07 | 0.74–5.78 | 0.167 |
Marital status | ||||||
Married | 1.00 | Reference | 1.00 | Reference | ||
Unmarried | 0.51 | 0.16–1.60 | 0.244 | 0.59 | 0.14–2.46 | 0.470 |
Widowed | 1.74 | 1.40–2.15 | 0.000 | 1.26 | 0.95–1.66 | 0.104 |
Divorced | 1.94 | 0.60–6.33 | 0.270 | 4.96 | 1.42–17.32 | 0.012 |
Pesticide exposure | 0.87 | 0.71–1.06 | 0.170 | 1.34 | 1.04–1.72 | 0.022 |
Dust exposure | 4.01 | 2.78–5.77 | 0.000 | 2.10 | 1.29–3.40 | 0.003 |
Irritant gas exposure | 4.05 | 1.38–11.85 | 0.011 | 2.87 | 0.76–10.84 | 0.119 |
Heavy metal exposure | 10.74 | 4.79–24.06 | 0.000 | 11.83 | 4.55–30.75 | 0.000 |
Family income, 1000 ¥ per year | ||||||
<10 | 1.00 | Reference | 1.00 | Reference | ||
10–49 | 1.41 | 1.09–1.82 | 0.008 | 1.44 | 1.07–1.95 | 0.018 |
50–99 | 0.86 | 0.59–1.24 | 0.413 | 1.12 | 0.73–1.72 | 0.611 |
100–149 | 0.48 | 0.28–0.82 | 0.007 | 0.86 | 0.48–1.57 | 0.631 |
150–199 | 0.21 | 0.07–0.68 | 0.009 | 0.17 | 0.02–1.23 | 0.079 |
≥200 | 0.90 | 0.39–2.09 | 0.799 | 1.29 | 0.50–3.38 | 0.600 |
Health insurance | 0.82 | 0.20–3.43 | 0.790 | 0.75 | 0.18–3.26 | 0.705 |
High blood pressure | 0.76 | 0.62–0.94 | 0.010 | 0.51 | 0.40–0.66 | 0.000 |
Hyperlipidemia | 1.41 | 0.94–2.11 | 0.093 | 1.36 | 0.83–2.21 | 0.225 |
Diabetes | 1.21 | 0.86–1.69 | 0.274 | 1.01 | 0.66–1.54 | 0.958 |
Family history of cataract | 17.82 | 9.48–33.48 | 0.000 | 14.80 | 6.98–31.37 | 0.000 |
Smoking | ||||||
Nonsmoker | 1.00 | Reference | 1.00 | Reference | ||
Current smoker | 0.47 | 0.34–0.64 | 0.000 | 0.82 | 0.53–1.25 | 0.346 |
Ex-smoker | 0.86 | 0.62–1.21 | 0.383 | 1.13 | 0.71–1.8 | 0.617 |
Alcohol drinking | ||||||
Nondrinker | 1.00 | Reference | 1.00 | Reference | ||
Current drinker | 0.71 | 0.55–0.91 | 0.007 | 1.28 | 0.92–1.77 | 0.144 |
Ex-drinker | 0.85 | 0.59–1.21 | 0.365 | 1.07 | 0.68–1.69 | 0.779 |
Physical activity | ||||||
None | 1.00 | Reference | 1.00 | Reference | ||
1–3 times per week | 2.95 | 1.99–4.35 | 0.000 | 3.00 | 1.92–4.67 | 0.000 |
>3 times per week | 2.32 | 1.85–2.92 | 0.000 | 1.73 | 1.30–2.29 | 0.000 |
Vitamin Ab | 2.72 | 0.62–11.88 | 0.183 | 3.49 | 0.67–18.34 | 0.139 |
β-caroteneb | 14.54 | 2.42–87.26 | 0.003 | 3.63 | 0.37–35.14 | 0.266 |
Vitamin Bb | 2.72 | 0.34–21.78 | 0.346 | 1.40 | 0.11–17.4 | 0.796 |
Vitamin Cb | 3.96 | 0.88–17.93 | 0.074 | 0.92 | 0.10–8.67 | 0.941 |
Vitamin Eb | 1.45 | 0.19–10.99 | 0.720 | 1.79 | 0.21–15.17 | 0.595 |
Calcium tabletsb | 1.29 | 0.93–1.79 | 0.133 | 1.17 | 0.79–1.72 | 0.434 |
Ironb | 1.55 | 0.20–11.83 | 0.671 | 2.39 | 0.30–19.32 | 0.415 |
Tea | 0.43 | 0.33–0.57 | 0.000 | 0.65 | 0.47–0.91 | 0.013 |
BMI, body mass index; CI, confidence interval; OR, odds ratio.
aAdjusted for sex, ethnicity, age, BMI, education, marriage status, pesticide, dust, irritant gas and heavy metal exposure, family income, health insurance, high blood pressure, hyperlipidemia, diabetes, family history of cataract, smoking, alcohol drinking, physical activity, and intake of vitamin A, β-carotene, vitamin B, vitamin C, vitamin E, calcium tablets and iron.
bDerived from only dietary supplements and not from diet.