Fig. 1.

Effect of native naringenin (NG) and heated naringenin (hNG) on splenocyte proliferation responses. Cells were incubated for 48 h with a increasing concentrations of samples without mitogen, b LPS (5 μg/ml) in the absence or presence of flavanones, or c lectin (5 μg/ml) in the absence or presence of flavanones. Control cells were incubated with RPMI 1640 only. Data shown are mean percentage proliferation (±SD) from three independent experiments. The statistical significance of results was evaluated by Student’s t test. ⁺ p < 0.05, value significantly different compared with control cells; *p < 0.05, value significantly different from molecularly treated cells