. 2016 Sep 30;5(10):3007–3017. doi: 10.1002/cam4.816

Table 1.

Concentrations of BCPO and BCP used in in vitro studies of BCP(O) anticancer activities

	Concentration (μg/mL)	Cell line	Author
BCPO
Isolated from Psidium cattleianum Sabine IC₅₀	0.87	HepG2	Jun et al. 28
	2.98	HeLa
	2.77	AGS
	3.69	SNU‐1
	6.03	SNU‐16
Isolated from Cinnamomum tamala leaves extract IC₅₀	8.94	A‐2780	Shahwar et al. 29
Isolated from Cinnamomum tamala leaves extract IC₅₀	7.19	BHK‐21	Shahwar et al. 29
Purchased from Sigma‐Aldrich IC₅₀	57.7	CaCo‐2	Ambrož et al. 31
Purchased from Jeju National University, Korea	6.6	KBM‐5, H1299, A293, U266, DU145	Kim et al. 37
Purchased from Jeju National University, Korea	6.6	PC‐3, MCF‐7	Park et al. 40
Purchased from Jeju National University, Korea	2.2	DU145, MDAMB‐231	Kim et al. 44
Purchased from Jeju National University, Korea	6.6	U266, MM1.S	Kim et al. 44
BCP
Isolated from essential oils of Aquilaria crassna IC₅₀	3.9	HCT 116	Dahham et al. 30
	5.5	PANC‐1
	12.9	HT‐29
	19.4	ME‐180
	21.3	PC3
	21.5	K562
	58.2	MCF‐7
IC₅₀ (source unknown)	64 lack of anticancer effects	DLD‐1/L‐929	Legault, Pichette32
Purchased from Sigma‐Aldrich	4.9 × 10⁻⁵	BS‐24‐1, MoFir	Amiel et al. 33

BCP(O) concentrations are shown as: IC₅₀, half maximal inhibitory concentration or the lowest concentration used exhibiting antiproliferative/cytotoxic activity. BCPO, β‐caryophyllene oxide; BCP, β‐caryophyllene.