Table 1.
Demographic and baseline characteristics (intention-to-treat population)
| Variable | Statistic | Methoxyflurane (N = 102) | Placebo (N = 101) | Total (N = 203) |
|---|---|---|---|---|
| Age (years) | n | 102 | 101 | 203 |
| Mean (SD) | 36.7 (13.9) | 35.7 (15.0) | 36.2 (14.4) | |
| Median | 35.0 | 30.0 | 33.0 | |
| Min, Max | 18, 74 | 18, 84 | 18, 84 | |
| Gender [n (%)] | Male | 53 (52.0) | 51 (50.5) | 104 (51.2) |
| Female | 49 (48.0) | 50 (49.5) | 99 (48.8) | |
| Race [n (%)] | White | 99 (97.1) | 96 (95.0) | 195 (96.1) |
| Asian | 1 (1.0) | 2 (2.0) | 3 (1.5) | |
| Black | 2 (2.0) | 2 (2.0) | 4 (2.0) | |
| Other | 0 | 1 (1.0) | 1 (0.5) | |
| Injury type (first injurya) | Burn | 0 | 3 (3.0) | 3 (1.5) |
| Contusion | 26 (25.5) | 22 (21.8) | 48 (23.6) | |
| Dislocation | 1 (1.0) | 2 (2.0) | 3 (1.5) | |
| Fracture | 19 (18.6) | 17 (16.8) | 36 (17.7) | |
| Injury due to foreign body | 2 (2.0) | 1 (1.0) | 3 (1.5) | |
| Laceration | 3 (2.9) | 5 (5.0) | 8 (3.9) | |
| Other | 51 (50.0) | 51 (50.5) | 102 (50.2) | |
| Site | Back | 5 (4.9) | 2 (2.0) | 7 (3.4) |
| Chest | 8 (7.8) | 0 | 8 (3.9) | |
| Face | 1 (1.0) | 0 | 1 (0.5) | |
| Left lower limb | 31 (30.4) | 25 (24.8) | 56 (27.6) | |
| Left upper limb | 11 (10.8) | 14 (13.9) | 25 (12.3) | |
| Other | 7 (6.9) | 5 (5.0) | 12 (5.9) | |
| Right lower limb | 29 (28.4) | 32 (31.7) | 61 (30.0) | |
| Right upper limb | 10 (9.8) | 23 (22.8) | 33 (16.3) | |
| VAS pain intensity (mm) | n | 100 | 99 | – |
| Mean (SD) | 66.2 (16.6) | 65.5 (18.1) | – | |
| Median | 68 | 70 | – | |
| Min, Max | 25, 100 | 10, 100 | – |
SD standard deviation, VAS visual analog scale
a11 patients had >1 injury; in these patients second injuries included contusions (seven patients), laceration (one patient) and ‘other’ (three patients), and third injuries included contusion (one patient) and laceration (one patient)