Table 4.
Global medication performance (intention-to-treat population)
| Methoxyflurane (N = 102) | Placebo (N = 101) | p value for treatment effect | |
|---|---|---|---|
| Patient assessment | |||
| n | 98 | 96 | |
| Excellent | 20 (20.4%) | 4 (4.2%) | |
| Very good | 22 (22.4%) | 6 (6.3%) | |
| Good | 34 (34.7%) | 20 (20.8%) | |
| Fair | 10 (10.2%) | 23 (24.0%) | |
| Poor | 12 (12.2%) | 43 (44.8%) | |
| Ordinal logistic regression | <0.0001 | ||
| Physician assessment | |||
| n | 55 | 54 | |
| Excellent | 6 (10.9%) | 0 | |
| Very good | 10 (18.2%) | 4 (7.4%) | |
| Good | 25 (45.5%) | 10 (18.5%) | |
| Fair | 8 (14.5%) | 20 (37.0%) | |
| Poor | 6 (10.9%) | 20 (37.0%) | |
| Ordinal logistic regression | <0.0001 | ||
| Research nurse assessment | |||
| n | 102 | 101 | |
| Excellent | 19 (18.6%) | 2 (2.0%) | |
| Very good | 20 (19.6%) | 6 (5.9%) | |
| Good | 35 (34.3%) | 18 (17.8%) | |
| Fair | 13 (12.7%) | 22 (21.8%) | |
| Poor | 15 (14.7%) | 53 (52.5%) | |
| Ordinal logistic regression | <0.0001 |
Significance of treatment effect was adjusted for baseline pain score