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Non-viral gene delivery systems toward the liver
| Method | Functional component |
| Lipids | Cationic lipids |
| Polymers | Cationic polymers |
| Proteins | Natural or chemically modified proteins in cationic nature |
| Peptides | Lysine or arginine residues in peptides |
| Needle injection | Mechanic force |
| Gene gun | Pressure |
| Electroporation | Electric pulse |
| Sonoporation | Ultrasound |
| Hydrodynamic delivery | Hydrodynamic pressure |
