Table 2.
Summary of the applications of hydrodynamic delivery for functional analysis of therapeutic genes related to the diseases of gastroenterology and hepatology
| Disease | Therapeutic Genes | Ref. |
| Nonalcoholic steatohepatitis | Inducible nitric oxcide synthetase | [8] |
| Hepatitis | HBV knockdown | [5,9] |
| HCV knockdown | ||
| Fulminant hepatitis | NKG2D knockdown | [7,10] |
| osteopontin knockdown | ||
| Liver injury | c-met | [7,11] |
| IL-37 | ||
| caspase knockdown | ||
| Liver fibrosis | platelet-derived growth factor receptor beta knockdown | [12] |
| Liver Regeneration | fibroblast growth factor 7 | [13] |
| Fabry disease | alpha-galactosidase A | [7] |
| Pancreatitis | pancreatitis associated protein 1 | [14] |
| Colon cancer | IL-15 | [15] |
HBV: Hepatitis B virus; HCV: Hepatitis C virus; IL: Interleukin.